RRM2--C2ORF48

Hyperlinks to databases below
COSMIC CHIMERKB CHIMERPUB CHIMERSEQ CHITARS
FARE-CAFE TICDB TUMOR_FUSION_GDPFusionCancerConjoinG
1000Genome18CancersBodymap2HPANon_Tumor_Cells
Babiceanu_DatasetBanned_DatasetKnown_FusionsONGene DatabaseBushman Cancer Gene Database
Tumor Gene Set By UniprotOesophagus_DatasetGliomas_DatasetProstate_DatasetPancreases_Dataset
GTExKlijn_DatasetFimereli_Dataset Literature Cortex_Dataset
ChromothripsisDB

Link to Genecards:

RRM2 C2ORF48

COSMIC

The fusion gene pair RRM2--C2ORF48 information is not available in COSMIC database.

ChimerKB

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The fusion gene pair RRM2--C2ORF48 information is not available in CHIMERKB (CHIMERDB 3.0) database.

ChimerPUB

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The fusion gene pair RRM2--C2ORF48 information is not available in CHIMERPUB (CHIMERDB 3.0) database.

ChimerSEQ

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The fusion gene pair RRM2--C2ORF48 information is not available in CHIMERSEQ (CHIMERDB 3.0) database.

ChiTaRS 2.1

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The fusion gene pair RRM2--C2ORF48 information is not available in CHITARS database.

FARE-CAFE

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The fusion gene pair RRM2--C2ORF48 information is not available in FARE-CAFE.

TicDB

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The fusion gene pair RRM2--C2ORF48 information is not available in TicDB.

TUMOR FUSION Gene Data Portal

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The fusion gene pair RRM2--C2ORF48 information is not available in TUMOR FUSION Gene Data Portal.

FusionCancer

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The fusion gene pair RRM2--C2ORF48 information is available in FusionCancer Database.
Database_IDHead_gene_symbolHead_breakpoint_locationTail_gene_symbolTail_breakpoint_locationCancer_typeSRA
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Acute myeloid leukemiaSRR620035
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Acute myeloid leukemiaSRR620042
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR069060
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR332281
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR332284
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387392
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387392
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387395
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387395
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387396
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387398
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387399
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387399
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387400
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387400
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387401
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387402
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387402
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387403
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387403
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387404
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387404
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387405
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387405
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387406
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387407
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387407
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387418
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387418
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387427
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387427
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387428
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387429
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387429
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387430
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387430
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387431
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387431
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387432
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387433
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387433
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387435
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387435
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387436
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387438
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387438
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387441
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387441
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387442
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387443
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387443
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387444
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387444
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387445
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387445
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387446
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Burkitt lymphomaSRR387446
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387447
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Burkitt lymphomaSRR387448
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Cervical cancerSRR315331
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Cervical cancerSRR315331
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Cervical cancerSRR315332
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315299
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315300
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315305
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315309
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315310
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315311
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315312
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR315336
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Chronic myelogenous leukemiaSRR387661
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR393760
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR393761
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR393766
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR393767
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Chronic myelogenous leukemiaSRR445374
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Colon cancerSRR364831
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Colon cancerSRR364831
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Hepatocellular cancerSRR307916
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Hepatocellular cancerSRR307926
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Lung cancerERR062337
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981Lung cancerERR164556
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Lung cancerERR164556
FUSC000112RRM2chr2:10269281C2orf48chr2:10281982Lung cancerERR164607
FUSC000112RRM2chr2:10269281C2orf48chr2:10281981MelanomaSRR354041

ConjoinG

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The fusion gene pair RRM2--C2ORF48 information is available in ConjoinG Database.
ConjoinG_IDChromosomemRNA_EST_AccessionsParent_Genes
CGHSA0554 2BM794489; BQ651088 RRM2 C2orf48

1000Genome

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Fusion gene RRM2--C2ORF48 has been found in a healthy sample. It has been found in RNA-seq data from some samples from 1000 genomes project (Greger et al., Tandem RNA Chimeras Contribute to Transcriptome Diversity in Human Population and Are Associated with Intronic Genetic Variants, Plos One, Aug 2014 ). A candidate fusion gene having this label has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

18Cancers

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Fusion gene RRM2--C2ORF48 is not found in a RNA-seq dataset of 18 types of cancers from 600 tumor samples (B. Alaei-Mahabadia et al., Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers, PNAS, Nov. 2016 )

Bodymap2

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Fusion gene RRM2--C2ORF48 is not found in the list of known false positive fusion genes. The list has been generated from healthy human samples collected from 16 organs from Illumina BodyMap2 RNA-seq database. A candidate fusion gene found in this list has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

HPA

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Fusion gene RRM2--C2ORF48 is not found in a healthy sample (RNA-seq database of 27 healthy tissues from 95 human individuals). A candidate fusion gene found in this dataset has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

Non_Tumor_Cells

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Fusion gene RRM2--C2ORF48 was found among the fusion genes which have been previously reported/found in non-tumor cell lines, like for example HEK293. These can considered as non-somatic mutation. [Fusion gene List compiled from FusionCatcher]

Babiceanu_Dataset

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The fusion gene pair RRM2--C2ORF48 information is available in Babiceanu_Dataset (Recurrent chimeric fusion RNAs in non-cancer tissues and cells, Nucl. Acids Res. (2016), doi: 10.1093/nar/gkw032).

Sample_sourceUp_geneUp_chrUp_strandUp_Genome_posDown_geneDown_chrDown_strandDown_Genome_poslocus-locusFusion_TypeDown_fusion_part_frame-shift_or_not
ESC RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
ESC RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
skin RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
skin RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
bone_marrow RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
bone_marrow RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
Lymph_node RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
Lymph_node RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift
bone_marrow RRM2 chr2 + 10269281 C2orf48 chr2 + 10281981 E/E INTRACHR-SS-0GAP frame-shift

Banned_Dataset

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Fusion gene RRM2--C2ORF48 is found in the list of known false positive fusion genes. A candidate fusion gene found in this list has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

Known_Fusions

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Fusion gene RRM2--C2ORF48 has not been found in the list of fusions previously reported or published in scientific articles/reports/books/abstracts/databases, indexed by Google, Google Scholar, PubMed, etc. The list has been manually curated by FusionCatcher software. This label has only the role to answer with YES or NO the question "has ever before a given (candidate) fusion gene been published or reported?". This label does not have in anyway the role to provide the original references to the original scientific articles/reports/books/abstracts/databases for a given fusion gene.[Fusion gene List compiled from FusionCatcher]

ONGene Database

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The head gene RRM2 is not a known oncogene according to ONGENE database.
The tail gene C2ORF48 is not a known oncogene according to ONGENE database.

Bushman Cancer Gene Database

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The head gene RRM2 is not cancer associated according to Bushman Cancer Gene database.
The tail gene C2ORF48 is not cancer associated according to Bushman Cancer Gene database.

Tumor Gene Set By Uniprot

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The head gene RRM2 is not a proto-oncogene or tumor suppresor gene according to Uniprot database.
The tail gene C2ORF48 is not a proto-oncogene or tumor suppresor gene according to Uniprot database.

Oesophagus_Dataset

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Fusion gene RRM2--C2ORF48 is not found in oesophageal tumors from TCGA samples, which are published here.

Gliomas_Dataset

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Fusion gene RRM2--C2ORF48 is not found in the RNA-seq dataset of 272 glioblastomas, published here.

Prostate_Dataset

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The fusion gene pair RRM2--C2ORF48 information is not available in Prostate Dataset (150 prostate tumor RNAs, Robison et al, Integrative Clinical Genomics of Advanced Prostate Cancer, Cell, Vol. 161, May 2015, http://dx.doi.org/10.1016/j.cell.2015.05.001).

Pancreases_Dataset

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Fusion gene RRM2--C2ORF48 is not found in pancreatic tumor dataset, published here.

GTEx

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Fusion gene RRM2--C2ORF48 has not been found in a healthy sample (GTEx database of healthy tissues (thru FusionAnnotator)). A candidate fusion gene found in this set has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

Klijin_Dataset

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The fusion gene pair RRM2--C2ORF48 information is not available in Klijn Dataset.

Fimereli_Dataset

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The fusion gene pair RRM2--C2ORF48 information is not found in Fimereli_Dataset.

Literature

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The fusion gene pair RRM2--C2ORF48 information is not found in known fusion genelist compiled from literature.

Cortex_Dataset

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Fusion gene RRM2--C2ORF48 is not found in Cortex_Dataset (Fusion genes found in healthy human brains (BA9 prefrontal cortex)) . A candidate fusion gene found in this dataset has a very high probability of being a false positive.

ChromothripsisDB

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The fusion gene pair RRM2--C2ORF48 information is not available in ChromothripsisDB database.