PAX8--PPARG

Hyperlinks to databases below
COSMIC CHIMERKB CHIMERPUB CHIMERSEQ CHITARS
FARE-CAFE TICDB TUMOR_FUSION_GDPFusionCancerConjoinG
1000Genome18CancersBodymap2HPANon_Tumor_Cells
Babiceanu_DatasetBanned_DatasetKnown_FusionsONGene DatabaseBushman Cancer Gene Database
Tumor Gene Set By UniprotOesophagus_DatasetGliomas_DatasetProstate_DatasetPancreases_Dataset
GTExKlijn_DatasetFimereli_Dataset Literature Cortex_Dataset
ChromothripsisDB

Link to Genecards:

PAX8 PPARG

COSMIC

The fusion gene pair PAX8--PPARG information is available in COSMIC database.

Link
PAX8--PPARG

ChimerKB

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The fusion gene pair PAX8--PPARG information is available in CHIMERKB (CHIMERDB 3.0) database.

Fusion_pair5'Gene Junction (Chr/Position/Strand)3'Gene Junction (Chr/Position/Strand)Breakpoint_TypeGenome_BuildDiseaseValidationPMIDGene TypeSource
PAX8_PPARG-/1355/ -/216/ Exonic hg19 - - - Receptor; Transcription_Factor Cosmic_recurrent
PAX8_PPARG-/1064/ -/216/ Exonic hg19 - - - Receptor; Transcription_Factor Cosmic_recurrent
PAX8_PPARG-/1253/ -/216/ Exonic hg19 - - - Receptor; Transcription_Factor Cosmic_recurrent
PAX8_PPARG-/943/ -/216/ Exonic hg19 - - - Receptor; Transcription_Factor Cosmic_recurrent
PAX8_PPARG-/-/ -/-/ - hg19 thyroid tumors - 16728576 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 papillary thyroid carcinoma - 20099311 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 papillary thyroid carcinoma - 20526288 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 papillary thyroid carcinoma - 20564403 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 thyroid carcinoma - 10958784 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 follicular thyroid carcinoma - 12161538 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 goitre - 12161538 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 follicular thyroid carcinoma - 12519876 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 goitre - 12519876 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 follicular thyroid carcinoma - 12970322 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 goitre - 12970322 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 thyroid tumors - 12170088 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 goitre - 12170088 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 follicular hurthle cell carcinoma - 22803838 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 papillary thyroid carcinoma - 16086077 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 follicular thyroid cancer - 19963130 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 thyroid cancer - 23436219 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 thyroid follicular neoplasm - 23881852 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 pediatric thyroid nodules - 23993207 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 follicular variant papillary carcinoma - 24277231 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 papillary thyroid cancer - 22895275 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 thyroid cancer - 22961909 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg19 hot thyroid nodules - 24915144 Receptor; Transcription_Factor Cosmic_nonrecurrent
PAX8_PPARG-/-/ -/-/ - hg18 adenocarcinoma - - Receptor; Transcription_Factor Mitelman
PAX8_PPARG-/-/ -/-/ - hg18 adenoma - - Receptor; Transcription_Factor Mitelman
PAX8_PPARG-/0/ -/0/ Exonic hg18 - - - Receptor; Transcription_Factor TICdb
PAX8_PPARG-/-/ -/-/ - hg18 thyroid carcinoma - 10958784 Receptor; Transcription_Factor OMIM

ChimerPUB

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The fusion gene pair PAX8--PPARG information is available in CHIMERPUB (CHIMERDB 3.0) database.

Fusion_pairTranslocationPMIDDiseaseValidationGene TypeSentence_highlight
PAX8_PPARG- 15256783goiter FISH;PCR;RT-PCR - Furthermore, none of the 6 FTCs, one follicular adenoma or one normal thyroid analyzed by fluorescence in situ hybridization (FISH) exhibited Pax8-PPAR gamma gene fusion. /// p25) translocation resulting in the expression of the Pax8-PPAR gamma fusion gene in patients with thyroid follicular carcinoma (FTC) occurs with high incidence (63%). /// p25) translocation generating Pax8-PPAR gamma fusion mRNA?. /// Pax8-PPAR gamma fusion mRNA was not detected in any FTC samples nor in the other samples. /// "In these carcinoma samples, the expression of mRNAs for the Pax8-PPAR gamma fusion product was analyzed by nested RT-PCR. "
PAX8_PPARG- 25069464thyroid nodule;thyroid carcinoma - - Most thyroid carcinomas contain one of several known driver mutations, such as the Val600Glu substitution in B-Raf, Ras mutations, RET gene fusions, or PAX8-PPARG gene fusions. /// "Most thyroid carcinomas contain one of several known driver mutations, such as the Val600Glu substitution in B-Raf, Ras mutations, RET gene fusions, or PAX8-PPARG gene fusions. " /// "The PAX8-PPARG gene fusion results in the production of a Pax-8-PPAR-? fusion protein (PPFP), which is found in approximately one-third of follicular thyroid carcinomas, as well as some follicular-variant papillary thyroid carcinomas. "
PAX8_PPARG- 15379724thyroid carcinoma;thyloid cancer - - We have confirmed that this Pax8/PPARgamma fusion gene (designated PPFP) is an oncogene, which accelerates cell growth, reduces rates of apoptosis and permits anchorage independent and contact uninhibited growth of a thyroid cell line. /// The PAX8/PPAR gamma fusion oncogene as a potential therapeutic target in follicular thyroid carcinoma..
PAX8_PPARGt(2;3)(q13;p25) / / 16609007thyroid carcinoma - - Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation. /// "Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.. "
PAX8_PPARG- 25629769thyroid nodule;thyroid carcinoma - - PAX8/PPARG and RET/PTC rearrangements were detected by real-time quantitative polymerase chain reaction, while BRAF and RAS mutations were detected by pyrosequencing. /// "PAX8/PPARG and RET/PTC rearrangements were detected by real-time quantitative polymerase chain reaction, while BRAF and RAS mutations were detected by pyrosequencing. "
PAX8_PPARG- 20578891anaplastic thyroid carcinoma - - These include PIK3CA mutations and genomic amplification/copy gain, Ras mutations, PTEN mutations, RET/PTC and PPARgamma/Pax8 rearrangements, as well as amplification/copy gain of PIK3CB, PDK1, Akt, and various receptor tyrosine kinase genes.
PAX8_PPARG- 24025583thyroid carcinoma;thyloid cancer - - A chromosomal translocation results in the production of a paired box 8-peroxisome proliferator-activated receptor gamma (PAX8-PPARG) fusion protein (PPFP) in ?35% of follicular thyroid carcinomas. /// The thyroid cancer PAX8-PPARG fusion protein activates Wnt/TCF-responsive cells that have a transformed phenotype.

ChimerSEQ

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The fusion gene pair PAX8--PPARG information is available in CHIMERSEQ (CHIMERDB 3.0) database.

Fusion_pair5'Gene Junction (Chr/Position/Strand)3'Gene Junction (Chr/Position/Strand)5'Gene_locus3'Gene_locusBreakpoint_TypeGenome_BuildFrameChr_infoCancertype_or_diseaseBarcodeIDGene TypeSource
PAX8_PPARGchr2/113994178/- chr3/12421203/+ 2q13 3p25.2 Exonic hg19 - Inter-chr THCA TCGA-BJ-A0YZ-01A Receptor; Transcription_Factor PRADA
PAX8_PPARGchr2/113992971/- chr3/12421203/+ 2q13 3p25.2 Exonic hg19 - Inter-chr THCA TCGA-DE-A4M9-01A Receptor; Transcription_Factor PRADA
PAX8_PPARGchr2/113992971/- chr3/12421203/+ 2q13 3p25.2 Exonic hg19 - Inter-chr THCA TCGA-EM-A3AJ-01A Receptor; Transcription_Factor PRADA
PAX8_PPARGchr2/113992971/- chr3/12421203/+ 2q13 3p25.2 Exonic hg19 - Inter-chr THCA TCGA-ET-A39N-01A Receptor; Transcription_Factor PRADA

ChiTaRS 2.1

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The fusion gene pair PAX8--PPARG information is not available in CHITARS database.

FARE-CAFE

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The fusion gene pair PAX8--PPARG information is available in FARE-CAFE.

Cancer Information
Fusion_ProteinCancer_TypeFP_Experimental_MethodFP_KaryotypeFP_Reference
PAX8-PPARG Follicular thyroid carcinoma FISH,RT-PCR t(2;3)(q13;p25) PubMed:10958784

Genomic Information
Fusion_ProteinFusion_Protein_Isoforms5'_ProteinF_B_PFBP_in_Exon/Intron5'_Protein_on_Positive/Negative_Strands3'_ProteinS_B_P3'_Protein_on_Positive/Negative_StrandsSBP_in_Exon/IntronFusion_Protein_mRNA_sequenceFusion_Protein_ReferenceFusion_Protein_GenbankID
PAX8-PPARG PAX8-PPARG-Isoform1 PAX8 _ _ 0 PPARG 12421200 1 0 ACCTACCCCGTGGTGGCAGaAATGACCATGGTTGACACA 10958784 _
PAX8-PPARG PAX8-PPARG-Isoform2 PAX8 _ _ 0 PPARG 12421200 1 0 ATCGCAGGCATGGTGGCAGAAaTGACCATGGTTGACACA 10958784 _
PAX8-PPARG PAX8-PPARG-Isoform3 PAX8 _ _ 0 PPARG 12421194 1 0 GGCCAGGCCCTCCTCTCAGaAATGACCATGGTTGACACA 10958784 _
PAX8-PPARG PAX8-PPARG-Isoform4 PAX8 _ _ 0 PPARG _ 1 _ CATGGTCATTtCTGAGAGGAGGG 12161538 _
PAX8-PPARG PAX8-PPARG-Isoform5 PAX8 _ _ 0 PPARG _ 1 _ CATGGTCATTtCTGCCACCACG 12161538 _
PAX8-PPARG PAX8-PPARG-Isoform6 PAX8 _ _ 0 PPARG _ 1 _ CATGGTCATTtCTGCCACCATGCCT 12161538 _
PAX8-PPARG PAX8-PPARG-Isoform7 PAX8 _ _ 0 PPARG _ 1 _ CATGGTCATTtCTGCCCCATGCCT 12161538 _
PAX8-PPARG PAX8-PPARG-Isoform8 PAX8 _ _ 0 PPARG _ 1 _ CATGGTCATTtCTGCTCGCCTTTGG 12161538 _

Domains and DDI Information
Fusion_ProteinFusion_Protein_IsoformsDomains_in_5'PartnerDDIs_for_Domains_in_5'PartnerDomains_in_3'PartnerDDIs_for_Domains_in_3'Partner5'_Protein5'P_Domains5'P_Domains_DDI_partners3'_Protein3'P_Domains3'P_Domains_DDI_partnersMissing_FP_DomainsMissing_FP_Domains_DDI
PAX8-PPARG PAX8-PPARG-Isoform1 - - 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
1) Ets
PAX8-PPARG PAX8-PPARG-Isoform2 - - 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
1) Ets
PAX8-PPARG PAX8-PPARG-Isoform3 - - 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
1) Ets
PAX8-PPARG PAX8-PPARG-Isoform4 - - - -PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
3) PPARgamma_N
4) zf-C4
5) Hormone_recep
1) Ets
2) zf-C4 , Hormone_recep
3) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8-PPARG PAX8-PPARG-Isoform5 - - - -PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
3) PPARgamma_N
4) zf-C4
5) Hormone_recep
1) Ets
2) zf-C4 , Hormone_recep
3) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8-PPARG PAX8-PPARG-Isoform6 - - - -PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
3) PPARgamma_N
4) zf-C4
5) Hormone_recep
1) Ets
2) zf-C4 , Hormone_recep
3) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8-PPARG PAX8-PPARG-Isoform7 - - - -PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
3) PPARgamma_N
4) zf-C4
5) Hormone_recep
1) Ets
2) zf-C4 , Hormone_recep
3) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
PAX8-PPARG PAX8-PPARG-Isoform8 - - - -PAX8 1) PAX
2) Pax2_C
1) Ets
PPARG 1) PPARgamma_N
2) zf-C4
3) Hormone_recep
1) zf-C4 , Hormone_recep
2) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1
1) PAX
2) Pax2_C
3) PPARgamma_N
4) zf-C4
5) Hormone_recep
1) Ets
2) zf-C4 , Hormone_recep
3) zf-C4 , Hormone_recep , fn3 , Arm , SRC-1

miRNA Information
Fusion_ProteinmiRNAs_Targets_Fusion_proteinMissing_MiRNAs_Targets_Fusion_proteinFP_miRNA_Validation_method
PAX8-PPARG hsa-miR-20b-5phsa-miR-27b-3phsa-miR-138-5phsa-miR-130a-3phsa-miR-130b-3phsa-miR-20a-5phsa-miR-1hsa-miR-215-5phsa-miR-192-5p _ Report assay,Western Blot,Microarray,qPCR

Transcription Factors Information
Fusion_Protein5'P_Ref_mRNA_seqIDFP_Transcription_factorsFP_Missing_TFsFP_TF_Reference
PAX8-PPARG NM_003466.3 1) RB1_HUMAN
2) RBL2_HUMAN
3) ZNF263_HUMAN
4) P53_HUMAN
5) ESTROGEN RECEPTOR ALPHA_HUMAN
6) ETS1_HUMAN
7) EGR1_HUMAN
8) FOS_HUMAN
9) GATA3_HUMAN
10) E2F1_HUMAN
11) CTCF_HUMAN
12) BRG1_HUMAN
13) HNF4A_HUMAN
14) TFAP2C_HUMAN
15) FOXA1_HUMAN
16) CEBPA_HUMAN
17) ESR2_HUMAN
18) ESR1_HUMAN
19) NR1H3_HUMAN
20) SPI1_HUMAN
21) TRIM24_HUMAN
1) CEBPA_HUMAN
2) STAT1_HUMAN
3) PRDM14_HUMAN
4) GATA2_HUMAN
5) TAL1_HUMAN
6) EPAS1_HUMAN
7) SETDB1_HUMAN
1) 20385362
2) 20385362
3) 19887448
4) 21394211
5) 20547749
6) 20019798
7) 20690147
8) 20139302
9) 21878914
10) 21310950
11) 21795385
12) 19505939
13) 21646355
14) 21572391
15) 21572391
16) 20219941
17) 21235772
18) 21566084
19) 22292898
20) 21241896
21) 21164480

TicDB

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The fusion gene pair PAX8--PPARG information is available in TICDB.
HeadGeneTailGenePubmedIDSequence
PAX8 PPARG 10958784 ACCTACCCCGTGGTGGCAGaAATGACCATGGTTGACACA
PAX8 PPARG 10958784 ATCGCAGGCATGGTGGCAGAAaTGACCATGGTTGACACA
PAX8 PPARG 10958784 GGCCAGGCCCTCCTCTCAGaAATGACCATGGTTGACACA
PAX8 PPARG 12161538 CATGGTCATTtCTGAGAGGAGGG
PAX8 PPARG 12161538 CATGGTCATTtCTGCCACCACG
PAX8 PPARG 12161538 CATGGTCATTtCTGCCACCATGCCT
PAX8 PPARG 12161538 CATGGTCATTtCTGCCCCATGCCT
PAX8 PPARG 12161538 CATGGTCATTtCTGCTCGCCTTTGG

TUMOR FUSION Gene Data Portal

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The fusion gene pair PAX8--PPARG information is available in TUMOR FUSION Gene Data Portal.
CancerTCGA_barcodeFusionPairEvalue5'Gene_Junction3'Gene_JunctionTierFrameTNWGS_validation
THCA BJ-A0YZ-01A PAX8__PPARG 1 2:113994178/-1 3:12421203/1 tier1 CDS-5UTR 12325 NA
THCA BJ-A0ZF-01A PAX8__PPARG 1 2:113992971/-1 3:12421203/1 tier1 CDS-5UTR 12326 NA
THCA DE-A4M9-01A PAX8__PPARG 1 2:113992971/-1 3:12421203/1 tier1 CDS-5UTR 12327 NA
THCA EM-A3AJ-01A PAX8__PPARG 1 2:113992971/-1 3:12421203/1 tier1 CDS-5UTR 12328 NA
THCA ET-A39N-01A PAX8__PPARG 1 2:113992971/-1 3:12421203/1 tier1 CDS-5UTR 12329 NA

FusionCancer

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The fusion gene pair PAX8--PPARG information is not available in FusionCancer Database.

ConjoinG

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The fusion gene pair PAX8--PPARG information is not available in ConjoinG Database.

1000Genome

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Fusion gene PAX8--PPARG has not been seen in a healthy sample (RNA-seq data from some samples from 1000 genomes project: Greger et al., Tandem RNA Chimeras Contribute to Transcriptome Diversity in Human Population and Are Associated with Intronic Genetic Variants, Plos One, Aug 2014 ). Therefore this candidate fusion gene has a low probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

18Cancers

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Fusion gene PAX8--PPARG is not found in a RNA-seq dataset of 18 types of cancers from 600 tumor samples (B. Alaei-Mahabadia et al., Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers, PNAS, Nov. 2016 )

Bodymap2

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Fusion gene PAX8--PPARG is not found in the list of known false positive fusion genes. The list has been generated from healthy human samples collected from 16 organs from Illumina BodyMap2 RNA-seq database. A candidate fusion gene found in this list has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

HPA

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Fusion gene PAX8--PPARG is not found in a healthy sample (RNA-seq database of 27 healthy tissues from 95 human individuals). A candidate fusion gene found in this dataset has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

Non_Tumor_Cells

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Fusion gene PAX8--PPARG was not found among the fusion genes which have been previously reported/found in non-tumor cell lines, like for example HEK293. The genes which are observed in those list can be considered as non-somatic mutation. [Fusion gene List compiled from FusionCatcher]

Babiceanu_Dataset

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The fusion gene pair PAX8--PPARG information is not available in Babiceanu_Dataset.

Banned_Dataset

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Fusion gene PAX8--PPARG is not found in the list of known false positive fusion genes. A candidate fusion gene found in this list has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

Known_Fusions

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Fusion gene PAX8--PPARG has been found in the list of fusions previously reported or published in scientific articles/reports/books/abstracts/databases, indexed by Google, Google Scholar, PubMed, etc. This label has only the role to answer with YES or NO the question "has ever before a given (candidate) fusion gene been published or reported?". This label does not have in anyway the role to provide the original references to the original scientific articles/reports/books/abstracts/databases for a given fusion gene.[Fusion gene List compiled from FusionCatcher]

ONGene Database

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The head gene PAX8 is a known oncogene according to ONGENE database.


The tail gene PPARG is a known oncogene according to ONGENE database.

Bushman Cancer Gene Database

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The head gene PAX8 is cancer associated according to Bushman Cancer Gene database.


The tail gene PPARG is cancer associated according to Bushman Cancer Gene database.

Tumor Gene Set By Uniprot

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The head gene PAX8 is not a proto-oncogene or tumor suppresor gene according to Uniprot database.
The tail gene PPARG is not a proto-oncogene or tumor suppresor gene according to Uniprot database.

Oesophagus_Dataset

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Fusion gene PAX8--PPARG is not found in oesophageal tumors from TCGA samples, which are published here.

Gliomas_Dataset

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Fusion gene PAX8--PPARG is not found in the RNA-seq dataset of 272 glioblastomas, published here.

Prostate_Dataset

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The fusion gene pair PAX8--PPARG information is not available in Prostate Dataset (150 prostate tumor RNAs, Robison et al, Integrative Clinical Genomics of Advanced Prostate Cancer, Cell, Vol. 161, May 2015, http://dx.doi.org/10.1016/j.cell.2015.05.001).

Pancreases_Dataset

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Fusion gene PAX8--PPARG is not found in pancreatic tumor dataset, published here.

GTEx

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Fusion gene PAX8--PPARG has not been found in a healthy sample (GTEx database of healthy tissues (thru FusionAnnotator)). A candidate fusion gene found in this set has a very high probability of being a false positive. [Fusion gene List compiled from FusionCatcher]

Klijin_Dataset

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The fusion gene pair PAX8--PPARG information is not available in Klijn Dataset.

Fimereli_Dataset

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The fusion gene pair PAX8--PPARG information is not found in Fimereli_Dataset.

Literature

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The fusion gene pair PAX8--PPARG information is not found in known fusion genelist compiled from literature.

Cortex_Dataset

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Fusion gene PAX8--PPARG is not found in Cortex_Dataset (Fusion genes found in healthy human brains (BA9 prefrontal cortex)) . A candidate fusion gene found in this dataset has a very high probability of being a false positive.

ChromothripsisDB

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The fusion gene pair PAX8--PPARG information is not available in ChromothripsisDB database.