Datasets used in FusionSearch module

Dataset Total unique head--tail fusion gene pair Dataset compiled from
COSMIC 293 COSMIC database (Forbes SA et al., 2016)
ChimerKB (ChimerDB 3) 1066 ChimerKB database (Lee et al., 2017)
ChimerPUB (ChimerDB 3) 2764 ChimerKB database (Lee et al., 2017)
ChimerSEQ (ChimerDB 3) 30002 ChimerKB database (Lee et al., 2017)
ChiTaRs 12790 ChiTaRs database (Frenkel-Morgenstern M et al., 2012)
FARE-CAFE 570 FARE-CAFE database (Korla PK et al., 2015)
TicDB 413 TicDB database (Novo FJ et al., 2007)
TUMOR_FUSION_GDP 18443 Tumor Fusion Gene Data Portal (K Yoshihara et al., 2014)
FusionCancer 4771 FusionCancer database (Wang Y et al., 2015)
ConjoinG 781 ConjoinG database (Prakash T et al., 2010)
1000Genome 112 Fusion genes observed in samples from 1000genome project. Compiled from FusionCatcher
18Cancers 4350 Fusion genes observed in a RNA-seq dataset of 18 tumor types (Alaei-Mahabadi et al., 2016)
Bodymap2 3035 List of fusion genes observed in healthy samples from 16 organs from Illumina Body Map RNAseq dataset (compiled from FusionCatcher )
HPA 7150 Human Protein Atlas dataset; RNA-seq dataser of 27 healthy tissues (Fagerberg et al., 2013)
Non_Tumor_Cells 5625 Fusions reported in non-tumor cell lines, compiled from FusionCatcher
Babiceanu_Dataset 4409 Fusion genes observed in non-cancer tissues and cells (Babiceanu et al., 2016)
Banned_Dataset 10112 List of fusion genes from healthy sample with strong supporting data (compiled from FusionCatcher )
Known_Fusions 7229 List of fusions known from literature (compiled from FusionCatcher )
Oesophagus_Dataset 1541 List of fusion genes seen in Oesophageal tumors from TCGA samples (Nature volume 541)
Gliomas_Dataset 185 Fusion genes observed in RNA-seq dataset of glioblastoms (p Zhao-Shi Bao et al., 2014)
Prostate_Dataset 2248 Fusion genes observed in RNA-seq data from 150 prostate tumors (Robinson et al., 2015)
Pancreases_Dataset 366 Fusion genes observed in pancreatic tumor samples (Bailey et al., 2016)
GTEx 68253 Fusion list observed in healthy tissues. Source is from GTEx database. A candidate fusion gene having this label has a very high probability of being a false positive. These fusion gene lists were compiled from FusionCatcher.
Klijn_Dataset 2201 List of fusion genes from human cancer cell lines (klijn et al., 2015)
Fimereli_Dataset 370 List of recurrent fusion genes in breast cancer (Fimereli et al., 2018)
Cortex_Dataset 737 Fusion genes found in healthy human brains (BA9 prefrontal cortex).
ChromothripsisDB 1534 ChromothripsisDB database
Literature - List of known fusion genes, compiled from literature
ONGene Database - Head and Tail partner of fusion gene is searched against ONGene database to check whether gene is known oncogene or not.
Bushman Cancer Gene Database - Head and Tail partner of fusion gene is searched against Bushman Cancer Gene Database to check whether gene is cancer associated or not
Tumor Gene Set By Uniprot - Head and Tail partner of fusion gene is searched against Uniprot database to check whether gene is proto-oncogene or tumor suppresor gene or not














































































Map